I posted this in Shana and Dana's Forum
Acupuncture works for depressed, pregnant women
- Bill
Acupuncture works for depressed, pregnant women
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Bill Glasheen
- Posts: 17299
- Joined: Thu Mar 11, 1999 6:01 am
- Location: Richmond, VA --- Louisville, KY
Bill, I dunno if my computer has remembered a cookie or something, but this link takes me to free full text. Here is the abstract at least:
http://journals.lww.com/greenjournal/Fu ... __A.7.aspx
Volume 201, Issue 6, Supplement, Page S19 (December 2009)
34: Acupuncture for depression during pregnancy
Rachel Manber1, Rosa Schnyer2, Andrea Chambers3, Deirdre Lyell1, Aaron Caughey4, Erin Carlyle3, Maurice Druzin1, Jenna Gress5, Mary Huang1, Tasha Kalista3, Robin Okada3, John Allen6
To assess the efficacy of acupuncture for depression during pregnancy in an evaluator-blinded randomized trial.
Study Design
return to Article Outline
150 participants who met DSM-IV criteria for Major Depressive Disorder were randomized to receive either acupuncture specific for depression (SPEC, n=52) or one of two active controls: control acupuncture (CTRL, n=49) or massage (MSSG, n=49). Treatments lasted eight weeks (12 sessions). Junior acupuncturists masked to treatment assignment needled participants at points prescribed by senior acupuncturists. Massage therapists and patients were not blinded. The primary outcome was the Hamilton Rating Scale for Depression, administered by blinded raters at baseline and after four and eight weeks of treatment. Data were analyzed using mixed effects models and by intent-to-treat.
Women who received SPEC experienced a significantly greater decrease in depression severity (p<0.05) compared to the combined controls (d=0.39, 95% CI [−1.31, 1.65]) or CTRL acupuncture alone (p<0.05; Cohen′s-d = 0.46, 95% CI [−1.24, 2.31]). They also had a higher response rate (63.0%) than the combined controls (44.3%; p<.05; NNT=5.3, 95% CI [2.8, 75.0]) or CTRL acupuncture alone (37.5%; p<0.05; NNT=3.9, 95% CI [2.2, 19.8]). Symptom reduction and response rates did not differ significantly between controls (CTRL 37.5% and MSSG 50.0%). Mild and transient side effects were reported by 43/150 participants (4 in MSSG; 19 in CTRL, 20 in SPEC). Significantly fewer participants reported side-effects in MSSG than the two acupuncture groups (p<0.01).
The benefits observed with eight weeks of SPEC acupuncture are clinically meaningful. The results suggest that the acupuncture protocol we tested could be a viable treatment option for depression during pregnancy.
http://journals.lww.com/greenjournal/Fu ... __A.7.aspx
Volume 201, Issue 6, Supplement, Page S19 (December 2009)
34: Acupuncture for depression during pregnancy
Rachel Manber1, Rosa Schnyer2, Andrea Chambers3, Deirdre Lyell1, Aaron Caughey4, Erin Carlyle3, Maurice Druzin1, Jenna Gress5, Mary Huang1, Tasha Kalista3, Robin Okada3, John Allen6
To assess the efficacy of acupuncture for depression during pregnancy in an evaluator-blinded randomized trial.
Study Design
return to Article Outline
150 participants who met DSM-IV criteria for Major Depressive Disorder were randomized to receive either acupuncture specific for depression (SPEC, n=52) or one of two active controls: control acupuncture (CTRL, n=49) or massage (MSSG, n=49). Treatments lasted eight weeks (12 sessions). Junior acupuncturists masked to treatment assignment needled participants at points prescribed by senior acupuncturists. Massage therapists and patients were not blinded. The primary outcome was the Hamilton Rating Scale for Depression, administered by blinded raters at baseline and after four and eight weeks of treatment. Data were analyzed using mixed effects models and by intent-to-treat.
Women who received SPEC experienced a significantly greater decrease in depression severity (p<0.05) compared to the combined controls (d=0.39, 95% CI [−1.31, 1.65]) or CTRL acupuncture alone (p<0.05; Cohen′s-d = 0.46, 95% CI [−1.24, 2.31]). They also had a higher response rate (63.0%) than the combined controls (44.3%; p<.05; NNT=5.3, 95% CI [2.8, 75.0]) or CTRL acupuncture alone (37.5%; p<0.05; NNT=3.9, 95% CI [2.2, 19.8]). Symptom reduction and response rates did not differ significantly between controls (CTRL 37.5% and MSSG 50.0%). Mild and transient side effects were reported by 43/150 participants (4 in MSSG; 19 in CTRL, 20 in SPEC). Significantly fewer participants reported side-effects in MSSG than the two acupuncture groups (p<0.01).
The benefits observed with eight weeks of SPEC acupuncture are clinically meaningful. The results suggest that the acupuncture protocol we tested could be a viable treatment option for depression during pregnancy.
--Ian
