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So while the briefcase with kevlar might work well as a universal shield, one may not be as protected against a knifing if that kevlar vest wasn't a composite with some other material or materials. Then again, it would be better than nothing.
Anyone remember chain mail?

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to grab the knife wielding hand
Kind of chancy. Attemptable if the dude is drunk or something and just hovering with it or slowly waves it around in front of your face during an interview. However, someone with a sharp knife and is a good fast slasher can really whip a knife around and easily remove fingers if he gets wind of what you are trying to do in time. I’ve been busted in the knuckles enough times trying to grab a short stickers wrist a-la-Kali style that I know already it’s not my favorite.
A good old fashioned Uechi circle block could come in handy followed through by a boshiken into the eye socket or a grab to the windpipe with a hiraken
could be good if the opportunity, timing, and distance presented itself and you didn’t screw up in the process. Uechi circle blocks
are fast and are a gross motor movement which provides broad coverage and don’t have to be accurate to get an arm out of the way. The deflection time also gives you something under a second to find and home in on a piece of face and attempt to destroy it. You’ve got one shot at it before the attacker recovers.
This is one place where I'd also recommend a good old fashioned TKD-style side-thrust kick or a 180-deg back kick directly into the sternum area with an upward angular component, really swinging the hips into it to minimize or nullify the target [you] area. This is one time to play the odds that the one closing the distance with a knife will be focused with one intent and not be thinking of something attacking him back, esp. from the lower body. This is the one of the very few times I'd nod approval to leaning away from the target while kicking. Legs are [usually] longer than an arm + knife.
However, neither the distance, opportunity, nor the timely registration in the defender's little brain of what's going on may allow for a potent side kick, but it is a man-stopper and is something to consider.
If you can’t use something from your own martial arts system, of which you may have thousands of hours invested, something you’d consider effective, then maybe it’s better to take you training elsewhere and switch systems.
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Allen Moulton from
Uechi-ryu Etcetera